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Migraines

A migraine can cause severe throbbing pain or a pulsing sensation, usually on just one side of the head. It's often accompanied by nausea, vomiting, and extreme sensitivity to light and sound.

Migraine Headache Clinical Trials

If you suffer from migraine headaches, you're not alone. About 12 percent of the U.S. population experience migraines, according to the National Institute of Neurological Disorders and Stroke (NINDS) at NIH. Migraines involve recurrent attacks of moderate to severe pain that is throbbing or pulsing and often strikes one side of the head. Untreated attacks last from 4 to 72 hours.

A great deal of research is currently underway testing new treatments for migraine headaches, some of which are designed to prevent migraine headaches altogether. Find out more about enrolling migraine headache clinical trials by selecting one of the below locations near you. Use the form on the page to schedule a free, in-office consultation to find out if a migraine headache clinical trial is right for you.

FIND CURRENTLY ENROLLING MIGRAINE HEADACHE CLINICAL TRIALS BY CLICKING ON A LOCATION NEAR YOU:


More About Migraine Headaches

Migraines occur most frequently in the morning, especially upon waking. Some people have migraines at predictable times, such as before menstruation or on weekends following a stressful week of work or a change in sleep schedule. Many people feel exhausted or weak following a migraine. Migraines often begin in childhood, adolescence or early adulthood. Migraines may progress through four stages: prodrome, aura, headache and post-drome, though you may not experience all stages.

Prodrome

One or two days before a migraine, you may notice subtle changes that warn of an upcoming migraine, including:

  • Constipation
  • Mood changes, from depression to euphoria
  • Food cravings
  • Neck stiffness
  • Increased thirst and urination
  • Frequent yawning

Aura

Aura may occur before or during migraines. Most people experience migraines without aura. Auras are symptoms of the nervous system. They are usually visual disturbances, such as flashes of light or wavy, zigzag vision. Sometimes auras can also be touching sensations (sensory), movement (motor) or speech (verbal) disturbances. Your muscles may get weak, or you may feel as though someone is touching you.

Each of these symptoms usually begins gradually, builds up over several minutes and lasts for 20 to 60 minutes. Examples of migraine aura include:

  • Visual phenomena, such as seeing various shapes, bright spots or flashes of light
  • Vision loss
  • Pins and needles sensations in an arm or leg
  • Weakness or numbness in the face or one side of the body
  • Difficulty speaking
  • Hearing noises or music
  • Uncontrollable jerking or other movements

Attack

A migraine usually lasts from four to 72 hours if untreated. The frequency with which headaches occur varies from person to person. Migraines may be rare, or strike several times a month. During a migraine, you may experience:

  • Pain on one side or both sides of your head
  • Pain that feels throbbing or pulsing
  • Sensitivity to light, sounds, and sometimes smells and touch
  • Nausea and vomiting
  • Blurred vision
  • Lightheadedness, sometimes followed by fainting

Post-drome

The final phase, known as post-drome, occurs after a migraine attack. You may feel drained and washed out, while some people feel elated. For about 24 hours, you may also experience:

  • Moodiness
  • Confusion
  • Dizziness
  • Weakness
  • Sensitivity to light and sound 

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